Uilyam Jeyms "Vilem" Defo (22-iyul, 1955-yilda tug‘ilgan) amerikalik aktyordir. U keng ko‘lamli va san'at filmlarida turli rollarni ijro etishdagi faoliyati bilan tanilgan. Defo ko‘plab mukofotlarga ega bo‘lib, ulardan biri eng yaxshi aktyor uchun Volpi kubogi va to‘rt Oskar, BAFTA mukofoti, to‘rt Zolotiy globus mukofoti, to‘rt Tanqidchilar tanlovi kino mukofoti va beshta Ekran aktyorlari gildiyasi mukofotlariga nomzod bo‘lgan. U Paul Schrader, Abel Ferrara, Lars von Trier, Julian Schnabel, Wes Anderson va Robert Eggers kabi rejissyorlar bilan tez-tez hamkorlik qilgan. Defo tajribaviy teatr kompaniyasi The Wooster Group asoschilaridan biridir. U 1980-yilda "Heaven's Gate" filmida nomi ko‘rsatilmagan rol bilan kino olamiga kirishgan. Defoning dastlabki faoliyati "The Loveless" (1982), "Streets of Fire" (1984) va "To Live and Die in L.A." (1985) filmlarida ishtirok etish bilan bog‘liq. U "Platoon" (1986) urush dramasi uchun birinchi Oskar nominatsiyasini oldi, keyin esa "Shadow of the Vampire" (2000), "The Florida Project" (2017) va "At Eternity's Gate" (2018) filmlaridagi rollari uchun nomzod bo‘ldi. Shuningdek, u "The Last Temptation of Christ" (1988) filmida Iso Masih rolidagi va "Spider-Man" (2002) superqahramon filmida Norman Osborn sifatidagi supervillain roli uchun keng tan olindi, bu rolni "Spider-Man 2" (2004) va "Spider-Man 3" (2007) davomi filmlarida ham ijro etgan, shuningdek, Marvel Kinematik Universidagi "Spider-Man: No Way Home" (2021) filmida ham qayta ijro etgan. Uning boshqa filmlardagi rollari "Mississippi Burning" (1988), "Born on the Fourth of July" (1989), "Wild at Heart" (1990), "Light Sleeper" (1992), "Body of Evidence" (1993), "Clear and Present Danger" (1994), "The English Patient" (1996), "Affliction" (1997), "New Rose Hotel" (1998), "Existenz" (1999), "The Boondock Saints" (1999), "American Psycho" (2000), "Auto Focus" (2002), "Finding Nemo" (2003), "The Life Aquatic with Steve Zissou" (2004), "Inside Man" (2006), "Mr. Bean's Holiday" (2007), "Antichrist" (2009), "Fantastic Mr. Fox" (2009), "Nymphomaniac" (2013), "The Fault in Our Stars" (2014), "John Wick" (2014), "The Grand Budapest Hotel" (2014), "Aquaman" (2018), "The Lighthouse" (2019), "Nightmare Alley" (2021), "Poor Things" (2023) va "Beetlejuice Beetlejuice" (2024) filmlarini o‘z ichiga oladi.
