Frédéric Testot Boulogne-Billancourt, Île-de-France shahrida tug‘ilgan va Korsikadagi Porto Vecchio shahrida o‘sib-ulg‘aygan. U Fun Radio’da Éric Judor va Ramzy Bedia (Éric et Ramzy) bilan ishlashni boshlagan, so‘ngra 1997 yilda Jamel Debbouze’ning dasturida Radio Nova’da birinchi marta Omar Sy bilan tanishgan. Ular birgalikda Canal+ telekanalida Debbouze’ning "Le Cinéma de Jamel" dasturida televidenie kareralarini boshladilar. Ular "Le Visiophon", "d'Omar et Fred", "Les sketches d'Omar et Fred" va "Les coming-nexts" kabi ko‘plab dasturlarni yaratdilar. Ikki yillik tanaffusdan so‘ng, 2005 yilda "Service après-vente des émissions" (inglizcha: "TV dasturlarining sotuvdan keyingi xizmati") nomli shou bilan qaytishdi. 2006 yildan 2012 yilgacha bu dastur Michel Denisot tomonidan olib boriladigan "Le Grand Journal"ning mashhur kundalik rubrikasiga aylandi. Testot keyinchalik bir nechta komediya filmlarida, jumladan "Sur la piste du Marsupilami" (2012), "The Big Bad Wolf" (2013) va "Arrête ton cinéma" (2016) filmlarida rol o‘ynadi va 2017 yilda Netflix Original Series "La Mante"da bosh rolni ijro etdi.
