Derek Siow — kino va televideniye aktyori bo'lib, "Angel Has Fallen", "The Beekeeper" va "Zero Dark Thirty" kabi badiiy filmlarda rol o'ynagan. U Josh Hartnett bilan birga "The Fear Index" nomli televizion trillerda paydo bo'lgan va "The Skinner Boys" animatsion teleserialining asosiy aktyorlaridan biri sifatida 2 mavsum davomida ishtirok etgan. Derek ko'plab video o'yinlarda ovoz berish bilan ham tanilgan, jumladan "Rise Of The Ronin", "Dead Island 2", "Star Wars: Battlefront 2", "Horizon Forbidden West", "Skull and Bones", "Gears Tactics", "Battlefield V", "Guitar Hero Live" va "Star Ocean: Anamnesis"da Ashton Anchors sifatida. Uning Gollivuddagi badiiy filmga kirishidagi debyuti Oskar mukofotiga sazovor bo'lgan "Zero Dark Thirty" filmida, Kathryn Bigelow bilan kichik rolda so'roqchi sifatida ishlagan. Keyinchalik, u Brad Pittning "War Machine" filmida AQSh dengiz kuchlari askari Tony Song sifatida paydo bo'ldi, Will Poulter, LaKeith Stanfield va Hopper Penn bilan birga. "The Rezort" filmida boy investor Jay Lee rolini o'ynadi. "Angel Has Fallen" filmida sobiq harbiy xaker sifatida muhim rol o'ynadi, Danny Huston bilan birga va "All The Old Knives" trillerida Thandiwe Newtonga qarshi CIA agenti Gene Wilcox sifatida tasvirlandi. Derek "Batgirl" filmida triad gangining rahbari sifatida J.K. Simmons (Komissar Gordon) bilan birga, shuningdek, "The Beekeeper" filmida Jason Stathamga qarshi Detektiv Chen sifatida rol o'ynadi. Derek "The Fear Index" (Josh Hartnett bilan birga) teleserialida texnologiya kompaniyasining CFOsi Lin Ju-Long sifatida, "The Capture" filmida politsiya kuchlari uchun matbuot xodimi Andy Sim sifatida va "American Odyssey" filmida amerikalik maxsus kuchlar askari Salter sifatida paydo bo'lgan. Derek Londonning Royal Academy of Dramatic Art akademiyasida tahsil olgan va shuningdek, Ivana Chubbuck Studio'da muntazam ravishda darslarga qatnashgan.
